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Selected Publications

Steinhilb ML, Dias-Santagata D, Fulga TA, Felch DL, Feany MB. Tau phosphorylation sites work in concert to promote tau neurotoxicity in vivoMol Bio Cell (2007) Dec; 18(12): 5060-8

Steinhilb ML, Dias-Santagata D, Mulkearns EE, Shulman JM, Biernat J, Mandelkow EM, Feany MB.  S/P and T/P phosphorylation is critical for tau neurotoxicity in DrosophilaJ Neurosci Res. (2007) May 1; 85(6): 1271-8

Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB.  Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivoNature Cell Biol. (2007) Feb; 9(2): 139-48

Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell cycle activation causes neurodegeneration in a Drosophila tauopathy model.  Curr Biol. (2006) Feb 7; 16(3): 230-41

King GD, Perez RG, Steinhilb ML, Gaut JR, Turner RS. X11alpha modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence. Neuroscience (2003) 120(1): 143-54

Ho CS, Marinescu V, Steinhilb ML, Gaut JR, Turner RS, Stuenkel EL. Synergistic effects of Munc18a and X11 proteins on amyloid precursor protein metabolism. J Biol Chem. (2002) Jul 26; 277(30): 27021-28

Steinhilb ML, Turner RS, Gaut JR. ELISA analysis of beta-secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways. J Neurochem. (2002) Mar; 80(6): 1019-28

Gau JT, Steinhilb ML, Kao TC, D’Amato CJ, Gaut JR, Frey KA, Turner RS. Stable beta-secretase activity and presynaptic cholinergic markers during progressive central nervous system amyloidogenesis in Tg2576 mice. Am J Pathol. (2002) 160(2): 731-8

Steinhilb ML, Turner RS, and Gaut JR. The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by beta-secretase. J Biol Chem. (2001) Feb 9; 276(6): 4476-84